Rich man's burden

Tree structured fiber optics MANs

Thomas Vicary and the Anatomie of Mans Body

Dysfunction of prefrontal cortex in schizophrenia includes changes in GABAergic mRNAs, including decreased expression of GAD1, encoding the 67 kDa glutamate decarboxylase (GAD67) GABA synthesis enzyme. The underlying molecular mechanisms remain unclear. Alterations in DNA methylation as an epigenetic regulator of gene expression are thought to play a role but this hypothesis is difficult to tes...

High cocoa polyphenol rich chocolate may reduce the burden of the symptoms in chronic fatigue syndrome

BACKGROUND Chocolate is rich in flavonoids that have been shown to be of benefit in disparate conditions including cardiovascular disease and cancer. The effect of polyphenol rich chocolate in subjects with chronic fatigue syndrome (CFS) has not been studied previously. METHODS We conducted a double blinded, randomised, clinical pilot crossover study comparing high cocoa liquor/polyphenol ric...

Gla-rich Protein (GRP): A New Player in the Burden of Vascular Calcification

Vascular calcification is a life-threatening complication of cardiovascular disease and an independent risk factor for morbidity and mortality. It is a complex and active cellular process that includes multiple players and regulators resembling physiological bone formation. Currently, it is generally accepted that our understanding of the molecular aetiology of vascular calcification remains in...

Artigos Schistosoma Mans Oni in Mice: Modulation of Granulomatous Response after Reinfection and Chemotherapeutic Treatment

Mice previously infected with Schistosoma mansoni, and cured by specific treatment (400ing/kg oxamniquine, p. o.) in the chronic phase o f the disease, were reinfected 20 days after treatment to assess their capacityfor modulation ofthe granulomatous response. Histopathologic examination o f the animals ’ liver, at 60 days after reinfection, evidenced the presence o f typical granulomas o f the...